We are in tireless pursuit of breakthroughs that improve patients' lives. We innovate each day to make the world a more healthy place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more innovative, attract and retain the best people, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We embody our purpose by finding the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.